- Sun exposure – UV radiations trigger the process of photoaging.
- Disturbance in the equilibrium status of oxidants & antioxidant defense system.
- Increased levels of oxidative Stress.
- Increased MMP-1 and MMP-3 which causes degradation of collagen fibers.
- Disturbed levels of antioxidants like L-Glutathione stimulating photoaging & hyperpigmentation.
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