1-boc Piperazine - Los Angeles

1-Boc Piperazine1-Boc-piperazine is a protected N-Boc piperazine. 1-Boc-piperazine is subject to Buchwald-Hartwig coupling with aryl Halides. 1-Boc-piperazine is prepared with the 80% range using N-Boc protection that is solvent-free and catalyzed by Iodine.

1-Boc piperazine is useful in the creation of (m-phenoxy)phenyl substituted piperazine derivatives. It can also be used to make the indazole inhibitors of DNA gyrase. Further, it plays an important role in the preparation of alfa,beta-poly(2-oxazoline) lipopolymers through living cationic ring opening polymerization. It is also involved in Buchwald-Hartwig coupling reactions the aryl halids.